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基因檢測標準品 > Mutation > CBP10525AI-Edigene® FLT3 p.I836del Reference Standard

AI-Edigene® FLT3 p.I836del Reference Standard
名稱 AI-Edigene® FLT3 p.I836del Reference Standard
型號 CBP10525
報價
特點 AI-Edigene&#174; FLT3 p.I836del Reference Standard Plus
  • 詳細內容
 CBP10525
FormatGenomic DNA
Description
FLT3 I836del results in the deletion of an amino acid in the protein kinase domain activation loop of the Flt3 protein at amino acid 836 (PMID: 12663439). I836del results in constitutive phosphorylation of Flt3 and activation of Stat5, Erk signaling, leading to transformation of cultured cells (PMID: 15256420).
  
Technical Data 
DNA Changec.2508_2510delCAT
AA Changep.I836del
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptNM_004119.3
Cosmic IDCOSM797
Chr position(GRCh37)chr13:28592637_28592639
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

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Storage4℃
Expiry36 months from the date of manufacture

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